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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

产品看起来并不太像一个鼻子,而是一个瓶子,装满了培养细菌的营养液体。但是给这个“鼻子”一个血液样本,让它嗅上一段时间,这个瓶子的斑点会改变颜色来表示它鉴别出的细菌种类。
戈尔迪·霍恩(Goldie Hawn)曾因影片《仙人掌花》(Cactus Flower)获最佳女配角奖,她的奖杯坐落在一个非常富有禅宗气息的地方——她的“印度房间”,她常在这里冥想。她的小金人并不是唯一一个和主人有共鸣的奖杯,罗素-克洛(Russell Crowe)曾在影片《角斗士》(Gladiator)中身着罗马战士裙装,扮演了一个威猛、极具感情和个性的古罗马战士--司令官马克西姆斯,他的奖杯放在鸡舍中,因为克洛相信小金人能够保佑母鸡下出更大的鸡蛋。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

In the 1990s, Roth applied it to the market for allocating US student doctors to hospitals. He developed a new algorithm that was adopted by the National Resident Matching Program, which helps match resident doctors with the right hospitals.
除了这一综合排行榜,《美国新闻与世界报道》还提供了地区、国家、特定专业大学排行榜,方便大家进行更为细致的搜索。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

The writer is a senior associate at the Carnegie Endowment and a former World Bank country director for China. Read other predictions for the world economy, politics and finance in 2012 at www.ft.com/thealist

Graphical abstract: Soft matter science and the COVID-19 pandemic
From the themed collection: 2019年公租房有效供应将加大
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

挖掘者认为这个墓地可追溯到1700年前,在当时的中国,库车在控制西部前线(西域)上扮演着关键的角色。由于丝绸之路的路线有经过西域,所以控制这个关键的区域对中国统治者来说是非常重要的。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Jackie Chan, a kung fu star and a member of the CPPCC National Committee, raised his experiences about smoking bans in China and Singapore as an example. During a business trip, his colleagues still smoked after a warning from a security guard in Zhuhai, Guangdong province, but they didn't dare smoke when they arrived in Singapore because "it was strict about smoking there".
His strategic shift away from corporate strategy was in spite of the fact that his own school had deterred him from making a career in education, even though he had worked as a private tutor.
The U.S. Veterans Day holiday also coincides with other World War One-era holidays around the world, including Remembrance Day in Britain and the Commonwealth nations of Australia and Canada.
optimistic

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

adj. 一致的,始终如一的
据《21世纪经济报道》称,广东去年的GDP增速为7.5%。
Exports to the EU, Japan and Hong Kong — which serves as a transit point for exports to many other parts of the world — fell by 4.1 per cent, 9.5 per cent and 12.2 per cent respectively.
The programme has enabled me to take a quantum leap in my career and prepared me to take on a strategic C-level [chief-level] role right after graduation, said another alumnus.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

北极和南极海冰量均降至历史最低水平

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

这家Post-it即时贴和思高(Scotch)胶带制造商在2月份授权进行120亿美元的股票回购,取代当前75亿美元的回购计划。《财富》美国500强公司3M公司(3M) 遵循了去年末发表的声明行动。这项声明称,公司在之后4年准备投入100亿美元用于收购,最多将投入220亿美元用于回购。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

Belgium and Uruguay are two diminutive countries that have maximized their advantages through inclusiveness, and of which Brazil, Argentina, Spain and Germany -- the quartet of forerunners for this year's title -- will rightly be wary. They, in the manner of Brazil's indigenous mosquitos and scorpions, are a useful reminder that small can often be deadly.
"这个家伙对当前情况作了利弊权衡:他有很大机会从故障电梯逃生,但是如果家庭作业没完成,他会很倒霉。"一名名为Zealshifang的用户调侃道。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

报告称,打造“机遇之城”的关键是技术创新和均衡发展。
恭贺新年。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

4.你的同事会泄密。
在综合榜单中,美国大学的数量最多,共有221所大学上榜。中国和日本分列第二、三名,上榜大学数量分别为136所和76所。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

adj. 谦虚的,适度的,端庄的
去年,在报名参考的139万人中,只有93万人最终进入了考场。
The Office for National Youth Campus Football said that China already had 13,381 "special football schools" as of 2016, and 69 counties are piloting programs for football in schools, the Xinhua News Agency reported.
时间:2009-09-16 编辑:vicki

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Buyers looking for new construction will have more options next year, as the number of new condos hitting the market in Manhattan, Brooklyn and Long Island City, Queens, is expected to more than double to 8,366 from 3,444 in 2014, according to data provided by Corcoran Sunshine Marketing Group.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

第六步 找到你的“花生”
因此,他在福布斯的该榜单上排名下滑了220位,与其他19名富豪并列第544位。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

读:游艇

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

The recession may be over, but the job market recovery is lagging way behind. And experts say the situation may get worse before it gets better.

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

n. 飞行员,领航员,引航员
不过,中国的手机制造商却在2016年实现了崛起。华为出货量同比增长了30.2%,达到了1.393亿台,再次排在全球第三。
10. Economics is killing the economy, but like coke addicts we won't stop
中国(大陆及香港)在排行榜上新添了25个成员,增长数量超过其他任何国家,共计207家。三个国家今年首次在排行榜上亮相了:毛里求斯、斯洛伐克以及多哥。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

But what will politicians actually do While President Trump is focused on bringing back traditional manufacturing jobs to America, different US states are experimenting with other policies to help low-paid precarious workers. These range from sharply higher minimum wages to new rules to stop employers changing staff schedules at the last minute.
产品看起来并不太像一个鼻子,而是一个瓶子,装满了培养细菌的营养液体。但是给这个“鼻子”一个血液样本,让它嗅上一段时间,这个瓶子的斑点会改变颜色来表示它鉴别出的细菌种类。
但是那数以千计的爱尔兰球迷呢?他们已经失控。
As stars such as Kevin Spacey and Morgan Freeman were alleged to have assaulted or harassed performers, activists began using the hashtag to share their ordeals online.
这家Post-it即时贴和思高(Scotch)胶带制造商在2月份授权进行120亿美元的股票回购,取代当前75亿美元的回购计划。《财富》美国500强公司3M公司(3M) 遵循了去年末发表的声明行动。这项声明称,公司在之后4年准备投入100亿美元用于收购,最多将投入220亿美元用于回购。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

8. Victoria and Abdul
“LBS has a great student body, very diverse in terms of nationality, competitive and intelligent,” commented one American graduate from the class of 2012. “It also gave me the opportunity to study in the US [on exchange] without having to do a purely US-focused American MBA.”

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

“…started swearing during the interview.”

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
From the themed collection: 卫浴定制成行业“风向标”
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

7. Smart cookie oven

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

据新华社报道,2015年教育部和其他5个中央政府部门一起组成了一个专门工作组,以保障足球在中国学校里的蓬勃发展。
Qube会提醒你注意垃圾回收,在垃圾最后被倒出来的时候进行监控,并告诉你更换空气清新剂。但这些人们通常可以通过嗅觉和其他感觉器官来判断。现在有一个300美元的“优雅”不锈钢,会不断用讨人厌的移动警报提醒你。
大型制药公司正在与美国癌症协会合作,以大幅折扣价为非洲患者提供抗癌药物。在整个非洲大陆,每年有45万人死于癌症,但其中有很多种癌症是可以治疗的,比如乳腺癌、宫颈癌和前列腺癌等。
4. How to draw manga

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

China has made huge progress in easing its residence and entry policies for foreigners since September 2015, which has helped attract more talent from overseas, as well as boost international exchanges and the economy, according to a ministry statement.
大力促进就业创业。
10. Economics is killing the economy, but like coke addicts we won't stop
去年我国内地人口总数达13.7亿,与2010年进行人口普查时相比,人口数量增加了3377万,这意味着人口年增长率为0.5%。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

9.亲爱的贵客们,我们希望英国能为你们贡献一个美好的夏天,这个夏天包括了顶尖的国际赛事、先进的设施、有趣的娱乐、以及汇集了几个世纪的艺术建筑精华的文化遗产。如果你最终只收获了四张卓著国际中心的摔跤比赛门票,好吧,祝你下次好运。
眼看11月就要过去了,正如我周一写的那样,往年经验表明,9支球队很有可能已经被踢出季后赛地竞争行列了。然而,他们中没有一支球队表明要摆烂。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
From the themed collection: 彻底打破楼市路径依赖
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

15. WeTransfer
谁都有不如意的时候,但是佳士得拍卖会上令人失望的情景已经不是第一次出现。今年7月的18世纪前绘画大师作品拍卖会仅拍得1900万英镑,而当时的最低预估价是3150万英镑。
The sales volume peaks at around 15 million per day, with nearly 700 tickets sold in every second.
Jackdaw Research的简?道森(Jan Dawson)表示,最近几个月“他表现得更加意气风发和充满自信”。
两名美国人因研究医生与医院、学生与学校和人体器官与被移植者之间的有效匹配,昨天被授予诺贝尔经济学奖。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

The Nobel Prize in physiology or medicine was awarded to a cellular-level experiment.
18 November
扫盲:Illuminati字面意思为“先觉者”,是启蒙运动时期的一个巴伐利亚秘密组织,成立于1776年5月1日。它的成员中包括文学巨匠歌德和哲学家海德这样声名赫赫的人物,但它存在的时间却十分短暂。我们熟知的Illuminati(光明会)最早的首脑,正是大名鼎鼎的伽利略。他非常喜爱对称物,于是另一位光照派成员——艺术大师贝尔尼尼便为伽利略设计了一件杰作。他将16世纪时人们认为组成世界的四大元素:土(earth)、水(water)、火(fire)、气(air)以及Illuminati(光明会)这五个原本并非对称字的单词设计成了对称的文字,即在倒转180度之后与原来的形状一模一样的文字图案。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

The requirements come from one of two newly issued regulations over the taxi and online ride-hailing services by China's transportation authority. The regulations will take effect in October and November respectively.
在家里创造一个属于自己的学习空间。如果身边家人都在身边,你就要确保大家都明白你是在里面学习,除非房子着火,他们是不会打扰到你的。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 2015年中国建材家居行业年终盘点
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

她的母亲,32岁的史蒂芬妮·博伊登称,波比非常有主角意识,听到别人叫她上台就会兴奋的跑过去,让她下台的时候就会愤怒的尖叫。
It was apparent not just in obvious brand extensions, like Banana Republic’s “Mad Men” collection (designed in collaboration with the show’s costume supremo, Janie Bryant), but in more pervasive, unspoken ways: in silhouette and print; in hemline and seam. And in the clear belief, visible on catwalks everywhere, that the 1960s were the answer to every moment of pallid inspiration, or aesthetic doubt.
每个句子后面有5个数字,选择最能反映你的感受的数字。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 东莞上周房价结构性回落
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

"This year is a key period for Tibet's war against poverty. We will continue mapping out policies and plans in accordance with varying situations and causes of poverty and increasing funds," said Lu.
据斯派克回忆,一天,拍摄工作结束后,另一位编剧詹妮弗·克里滕登在走廊叫住他,问:"你一定要这样吗?你确定这样不会毁了朱莉娅的前程吗?"考虑到当年朱莉娅凭此剧获得艾美奖,我们不妨说这场舞戏其实让这位女演员在演艺事业上更进了一步。为了怀旧,您不妨抽空再去回顾一下伊莱恩和她著名的"伊莱恩舞步"。
com共同,bat打,击-共同打-战斗com bat:共同生活的bat蝙蝠,免不了要combat

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 杭州进一步加强房地产中介监管
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

批评人士一直急于指出,库克对新产品开发的参与度不如他前任那样高,而且当他走上舞台介绍新品时,也无法引起同样的兴奋。但库克知道自己的短处,他从健身和时尚界招揽人才,组建了一支新团队,其中包括前博柏利(Burberry)首席执行官安杰拉?阿伦茨(Angela Ahrendts),以及工业设计师马克?纽森(Marc Newson)。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

因城施策去库存。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

去年2月份中国国家旅游局启用一个名为“美丽中国”的标志,意在向海外宣传推广其旅游形象,然而有人讽刺“美丽中国”这一名称与中国城市在严重污染之下那一张张“不太美丽”的照片相比反差太大。希望专家们今后能设计出一个好一点的方案来。
“目前市场上有大量尖端,环保的人造皮草,我相信你会同意现在没有任何借口来杀死动物以获取皮草了。”

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

林怡仲预测道,下半年A股IPO的数量或将维持与上半年相当,预计2016年全年A股IPO为120宗左右,融资规模在600-800亿元人民币左右。
单词capacity 联想记忆:
8. How to dip dye hair
scary puppy like head tilts and glares

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

de去掉,but。去掉but?导演Z(平静):你可以上台了。女演员F:but我还没准备好呢?Z(有点儿烦):哪那么多事儿呀,快点儿!F:but我这可是第一次!Z(强忍):谁没有第一次呀,快!F:but…,Z(已经怒了):哪XX那么多but呀,全都给我de掉,再不上去我就X人了!!!
The Global Obesity Epidemic

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
From the themed collection: 广东:高端人才个税最高15%
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

‘Jeopardy!’ This game show celebrated the 50th anniversary of its debut (broadcast on March 30, 1964), and proved it can still not only stump viewers but also surprise them. That’s not just because the host, Alex Trebek, briefly regrew a mustache after 13 clean-shaven years, but also because some contestants showed they could still rile an audience. This year, it was Arthur Chu, who introduced a blitzkrieg style of gamesmanship that provoked a cyber hate-fest. His strategy was thrilling and certainly effective: he came in second in the Tournament of Champions. (Ben Ingram, the nice guy, finished first.)
But markets plunged following the ECB decision. Investors complained that the central bank had misled markets about the amount of extra stimulus it was prepared to inject to shore up the recovery.

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

2.全球谋杀案

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

adj. 有资格的,有限制的
十年来,每年年初我都会从上一年企业界惊现的胡说八道中评选出个中翘楚。我常常乐此不疲。今年我发现那些委婉语、拧巴话、不知所谓的表达还有赤裸裸的恶心话在水准上普遍很不给力,所以我决定2016年度“金废话奖”(Golden Flannel Awards)要从一个比较来劲的奖项——大白话奖——讲起。
200911/90348.shtmlHere are the 10 winners of the 2012 Ig Nobel Prizes given to scientists, writers, and peacemakers who make silly but thoughtful contributions to the world, or as the Annals of Improbable Research puts it, "first make people laugh, and then make them think." I can vouch for them making us laugh!
We will continue to encourage people to start businesses and make innovations.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 西宁市住房公积金政策有调整
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

《ScreamRide》
女王每次都是飞机一停就像子弹一样迅速下飞机。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

5. bedazzled / a . 眼花缭乱的。
19. Going, Going, Almost Gone Quentin Tarantino shot his latest, “The Hateful Eight,” in 70 millimeter, and the film is slated to play in almost 100 theaters that, like most of rooms across the country, now usually use digital projection. Whatever you think of Mr. Tarantino, try to catch “The Hateful Eight” on film so you can see for yourself how the industry-enforced switch to digital has radically changed movies.
The programme entered the ranking in second place in 2006 and was ranked top in 2008.

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 智能家居缺乏统一标准成发展瓶颈
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Stand: Costco CEO Craig Jelinek refused to open on Thanksgiving Day
All employees receive a $25 monthly credit to the DreamWorks PrintCenters at the Glendale and Redwood City campuses. Charged only for supplies, the studio is able to offer inexpensive services that range from printing photographs to creating greeting cards and personalized calendars.
日前,美国一位母亲为她14岁的、因在视频游戏中作弊而面临指控的儿子,写信进行辩护。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

It is also reported that Chinese citizens made 1.26 billion cinema visits in 2015, a roughly 51 percent increase from a year earlier.
re反,treat=tract拉-拉回-撤退

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
From the themed collection: 家具:进口价格不敌代购
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

未来数年时间内,截止2018年,支出将上升至1.3万亿美元。而1000亿美元的丙型肝炎药物支出及同等的癌症治疗费用,还有780亿美元的糖尿病治疗费用都将是构成支出上升的因素。
单词document 联想记忆:
The Peoria, Ill.-based maker of heavy equipment authorized $10 billion in stock repurchases in January and expected to buy back $1.7 billion of its shares in the first quarter this year to complete its previous $7.5 billion repurchase initiative. The ongoing buybacks are "a result of our record cash flow," said CEO Doug Oberhelman.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

“I?.?.?.?learnt to interact with people from other cultures and other places in society,” noted one Swedish graduate.
If the answer is "yes", then maybe you are a Type D personality.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

In contrast, the nation witnessed a tumbling trend for minivans, whose volume totaled 71,300 units, a 31 percent drop year-on-year.
4. How to draw manga
Haruhiko Kuroday, the Japanese central bank governor said: “I think we can be cautiously optimistic about the global outlook.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

v. 构成,把 ...

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

根据人社部、财政部近日联合下发的通知,企业和机关事业单位退休人员的月均养老金将在2016年的基础上上调约5.5%。
Taiwan Semiconductor Manufacturing Company (TSMC).” Previous reports have pegged the screen size at just under the 5 inches of Samsung’s Galaxy 4.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

苹果公司可以推出一款售价2,000元人民币(330美元)的迷你iPhone,这样就能和联想(Lenovo)、华为(Huawei)、中兴(ZTE)和酷派(Coolpad)的旗舰产品相抗衡了。
这让11月份的贸易顺差达到446.1亿美元,比10月份减少约44.5亿美元,低于预期。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

On the long voyage to World Cup triumph, Belgium and Uruguay are two icebergs that the favorites would rather avoid. Both nations, despite being underdogs in this year's tournament, have the ability and the nous to upset their bigger and brasher rivals. Yet it's remarkable, given their small size and history as geopolitical doormats, that they remain competitive at all.
Beijing Capital International Airport performed slightly better, with its punctuality rate reaching 60.7%.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

周三,北京市发改委主任卢彦在新闻发布会上说:“我们将会在通州开展297个项目,例如建设地铁线和高速路及改善生态环境。”
Essentially this reform will help the government to focus on performing its due role more effectively instead of overreaching itself, because that will only tie down our businesses, cut government’s efficiencies and even public credibility.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

“中日关系说到底,就是日本能不能接受中国的发展壮大,这是根本问题。”

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

007系列电影主题曲第九名:露露--《金枪人》
"People should just never walk away and leave their animals," Ms Lewis said. "Everyone has a legal obligation to look after animals in their care."
“What happens if one of these Airbnb guests starts a fire?” asked Phyllis H. Weisberg, chairwoman of the Cooperative and Condominium Law Committee at the New York City Bar Association. “Who’s paying for that?”
In the book, Galore moves in with Bond in London and together they spend their mornings squabbling.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

Dachis says: Adidas added more than 34 million new fans and followers in just 12 months this year. The company put that audience to good use and benefited from high levels of positive discussion all year long.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 抑制非理性学区平房交易
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

6.头戴式电脑出现
劳瑞斯蒂尔
这项任命是由澳大利亚贸易、旅游与投资部长史蒂文·乔博于2月21日宣布的。中国国家旅游局局长李金早出席了该活动。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

Next year, more tech workers will speak out, following former Facebook employees Sean Parker and Chamath Palihapitiya, who have condemned social media’s addictive properties.
请接受我们对你及你全家的美好祝福,祝你们新年快乐。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

The web portal, which has put mobile technology at the heart of a plan to turn around its struggling fortunes, has turned to British teenager Nick D’Aloisio and Summly, which automatically summarises news stories for the small screen.
Consoles: Xbox One

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

支持:洛杉矶影评人协会将其评为最佳影片。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Given the Raptors' existing personnel, the Ibaka/Tucker additions qualify as massive defensive upgrades, giving coach Dwane Casey the tools he will need to grind out postseason wins if Lowry and DeMar DeRozan see their scoring efficiency dip as it has in years past.
The International Organization for Migration says the number of migrants and refugees entering Europe in 2015 has gone over the one million mark, the largest influx of its kind since the end of World War Two.
Yes. Mr Modi’s overnight ban on using high-value bank notes was a big shock, and seriously disrupted the economy. But it delivered rich political rewards, bolstering the premier’s image as a decisive leader willing to take tough action against corruption. With the next general elections due in 2019, Mr Modi will be tempted to deliver one more big bang to dazzle voters. Watch out for dramatic action against wealthy individuals holding properties in others’ names to hide their ownership.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

vt. 使成为可取,
6.I’m 29. – Because 29 is like 20 years younger than 30.
The identity of the people buried in the cemetery is a mystery. The cemetery had been robbed in the past and no writing was found that indicates the names of those buried or their positions in life.
Halloween is just a few days away. Which means, if you haven’t gotten your costume or decorations sorted out yet, you might want to start doing that pretty soon.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

《生活真奇怪》
The banks' ability to return money to shareholders have declined. The slowing earning growth, high nonperforming loans and required deposits on the reserve have placed pressure on the banks in regards to capital supplement, said Guo Tianyong, director of the China Banking Research Center at the Central University of Finance and Economics.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

delicate
The memes included jokes about pedophilia, child abuse, sexual assault, and the Holocaust.
1.水上类比赛项目

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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About this collection

During the same period, Braziland Russia slashed their holdings to USD 261.7 billion and USD 108.9 billion,respectively.
3.解决问题的好手

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