Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
戈尔迪·霍恩（Goldie Hawn）曾因影片《仙人掌花》（Cactus Flower）获最佳女配角奖，她的奖杯坐落在一个非常富有禅宗气息的地方——她的“印度房间”，她常在这里冥想。她的小金人并不是唯一一个和主人有共鸣的奖杯，罗素-克洛（Russell Crowe）曾在影片《角斗士》（Gladiator）中身着罗马战士裙装，扮演了一个威猛、极具感情和个性的古罗马战士--司令官马克西姆斯，他的奖杯放在鸡舍中，因为克洛相信小金人能够保佑母鸡下出更大的鸡蛋。
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
In the 1990s, Roth applied it to the market for allocating US student doctors to hospitals. He developed a new algorithm that was adopted by the National Resident Matching Program, which helps match resident doctors with the right hospitals.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
The writer is a senior associate at the Carnegie Endowment and a former World Bank country director for China. Read other predictions for the world economy, politics and finance in 2012 at www.ft.com/thealist
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Jackie Chan, a kung fu star and a member of the CPPCC National Committee, raised his experiences about smoking bans in China and Singapore as an example. During a business trip, his colleagues still smoked after a warning from a security guard in Zhuhai, Guangdong province, but they didn't dare smoke when they arrived in Singapore because "it was strict about smoking there".
His strategic shift away from corporate strategy was in spite of the fact that his own school had deterred him from making a career in education, even though he had worked as a private tutor.
The U.S. Veterans Day holiday also coincides with other World War One-era holidays around the world, including Remembrance Day in Britain and the Commonwealth nations of Australia and Canada.
Trends and targets in antiviral phototherapy
Exports to the EU, Japan and Hong Kong — which serves as a transit point for exports to many other parts of the world — fell by 4.1 per cent, 9.5 per cent and 12.2 per cent respectively.
The programme has enabled me to take a quantum leap in my career and prepared me to take on a strategic C-level [chief-level] role right after graduation, said another alumnus.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Belgium and Uruguay are two diminutive countries that have maximized their advantages through inclusiveness, and of which Brazil, Argentina, Spain and Germany -- the quartet of forerunners for this year's title -- will rightly be wary. They, in the manner of Brazil's indigenous mosquitos and scorpions, are a useful reminder that small can often be deadly.
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
The Office for National Youth Campus Football said that China already had 13,381 "special football schools" as of 2016, and 69 counties are piloting programs for football in schools, the Xinhua News Agency reported.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Buyers looking for new construction will have more options next year, as the number of new condos hitting the market in Manhattan, Brooklyn and Long Island City, Queens, is expected to more than double to 8,366 from 3,444 in 2014, according to data provided by Corcoran Sunshine Marketing Group.
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
The recession may be over, but the job market recovery is lagging way behind. And experts say the situation may get worse before it gets better.
Antiviral drug discovery: broad-spectrum drugs from nature
10. Economics is killing the economy, but like coke addicts we won't stop
Influenza neuraminidase: A druggable target for natural products
But what will politicians actually do While President Trump is focused on bringing back traditional manufacturing jobs to America, different US states are experimenting with other policies to help low-paid precarious workers. These range from sharply higher minimum wages to new rules to stop employers changing staff schedules at the last minute.
As stars such as Kevin Spacey and Morgan Freeman were alleged to have assaulted or harassed performers, activists began using the hashtag to share their ordeals online.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
8. Victoria and Abdul
“LBS has a great student body, very diverse in terms of nationality, competitive and intelligent,” commented one American graduate from the class of 2012. “It also gave me the opportunity to study in the US [on exchange] without having to do a purely US-focused American MBA.”
The role of biosensors in the detection of emerging infectious diseases
“…started swearing during the interview.”
Quantitative determination of mechanical stability in the novel coronavirus spike protein
7. Smart cookie oven
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
4. How to draw manga
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
China has made huge progress in easing its residence and entry policies for foreigners since September 2015, which has helped attract more talent from overseas, as well as boost international exchanges and the economy, according to a ministry statement.
10. Economics is killing the economy, but like coke addicts we won't stop
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Inhibition of SARS coronavirus helicase by bismuth complexes
The sales volume peaks at around 15 million per day, with nearly 700 tickets sold in every second.
Jackdaw Research的简?道森(Jan Dawson)表示，最近几个月“他表现得更加意气风发和充满自信”。
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
The Nobel Prize in physiology or medicine was awarded to a cellular-level experiment.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
The requirements come from one of two newly issued regulations over the taxi and online ride-hailing services by China's transportation authority. The regulations will take effect in October and November respectively.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
It was apparent not just in obvious brand extensions, like Banana Republic’s “Mad Men” collection (designed in collaboration with the show’s costume supremo, Janie Bryant), but in more pervasive, unspoken ways: in silhouette and print; in hemline and seam. And in the clear belief, visible on catwalks everywhere, that the 1960s were the answer to every moment of pallid inspiration, or aesthetic doubt.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
"This year is a key period for Tibet's war against poverty. We will continue mapping out policies and plans in accordance with varying situations and causes of poverty and increasing funds," said Lu.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
批评人士一直急于指出，库克对新产品开发的参与度不如他前任那样高，而且当他走上舞台介绍新品时，也无法引起同样的兴奋。但库克知道自己的短处，他从健身和时尚界招揽人才，组建了一支新团队，其中包括前博柏利(Burberry)首席执行官安杰拉?阿伦茨(Angela Ahrendts)，以及工业设计师马克?纽森(Marc Newson)。
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
8. How to dip dye hair
scary puppy like head tilts and glares
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
The Global Obesity Epidemic
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
‘Jeopardy!’ This game show celebrated the 50th anniversary of its debut (broadcast on March 30, 1964), and proved it can still not only stump viewers but also surprise them. That’s not just because the host, Alex Trebek, briefly regrew a mustache after 13 clean-shaven years, but also because some contestants showed they could still rile an audience. This year, it was Arthur Chu, who introduced a blitzkrieg style of gamesmanship that provoked a cyber hate-fest. His strategy was thrilling and certainly effective: he came in second in the Tournament of Champions. (Ben Ingram, the nice guy, finished first.)
But markets plunged following the ECB decision. Investors complained that the central bank had misled markets about the amount of extra stimulus it was prepared to inject to shore up the recovery.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
十年来，每年年初我都会从上一年企业界惊现的胡说八道中评选出个中翘楚。我常常乐此不疲。今年我发现那些委婉语、拧巴话、不知所谓的表达还有赤裸裸的恶心话在水准上普遍很不给力，所以我决定2016年度“金废话奖”(Golden Flannel Awards)要从一个比较来劲的奖项——大白话奖——讲起。
200911/90348.shtmlHere are the 10 winners of the 2012 Ig Nobel Prizes given to scientists, writers, and peacemakers who make silly but thoughtful contributions to the world, or as the Annals of Improbable Research puts it, "first make people laugh, and then make them think." I can vouch for them making us laugh!
We will continue to encourage people to start businesses and make innovations.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
5. bedazzled / a . 眼花缭乱的。
19. Going, Going, Almost Gone Quentin Tarantino shot his latest, “The Hateful Eight,” in 70 millimeter, and the film is slated to play in almost 100 theaters that, like most of rooms across the country, now usually use digital projection. Whatever you think of Mr. Tarantino, try to catch “The Hateful Eight” on film so you can see for yourself how the industry-enforced switch to digital has radically changed movies.
The programme entered the ranking in second place in 2006 and was ranked top in 2008.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Stand: Costco CEO Craig Jelinek refused to open on Thanksgiving Day
All employees receive a $25 monthly credit to the DreamWorks PrintCenters at the Glendale and Redwood City campuses. Charged only for supplies, the studio is able to offer inexpensive services that range from printing photographs to creating greeting cards and personalized calendars.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
It is also reported that Chinese citizens made 1.26 billion cinema visits in 2015, a roughly 51 percent increase from a year earlier.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
The Peoria, Ill.-based maker of heavy equipment authorized $10 billion in stock repurchases in January and expected to buy back $1.7 billion of its shares in the first quarter this year to complete its previous $7.5 billion repurchase initiative. The ongoing buybacks are "a result of our record cash flow," said CEO Doug Oberhelman.
A modular microarray imaging system for highly specific COVID-19 antibody testing
“I?.?.?.?learnt to interact with people from other cultures and other places in society,” noted one Swedish graduate.
If the answer is "yes", then maybe you are a Type D personality.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
In contrast, the nation witnessed a tumbling trend for minivans, whose volume totaled 71,300 units, a 31 percent drop year-on-year.
4. How to draw manga
Haruhiko Kuroday, the Japanese central bank governor said: “I think we can be cautiously optimistic about the global outlook.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
v. 构成，把 ...
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Taiwan Semiconductor Manufacturing Company (TSMC).” Previous reports have pegged the screen size at just under the 5 inches of Samsung’s Galaxy 4.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
On the long voyage to World Cup triumph, Belgium and Uruguay are two icebergs that the favorites would rather avoid. Both nations, despite being underdogs in this year's tournament, have the ability and the nous to upset their bigger and brasher rivals. Yet it's remarkable, given their small size and history as geopolitical doormats, that they remain competitive at all.
Beijing Capital International Airport performed slightly better, with its punctuality rate reaching 60.7%.
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Essentially this reform will help the government to focus on performing its due role more effectively instead of overreaching itself, because that will only tie down our businesses, cut government’s efficiencies and even public credibility.
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
"People should just never walk away and leave their animals," Ms Lewis said. "Everyone has a legal obligation to look after animals in their care."
“What happens if one of these Airbnb guests starts a fire?” asked Phyllis H. Weisberg, chairwoman of the Cooperative and Condominium Law Committee at the New York City Bar Association. “Who’s paying for that?”
In the book, Galore moves in with Bond in London and together they spend their mornings squabbling.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Dachis says: Adidas added more than 34 million new fans and followers in just 12 months this year. The company put that audience to good use and benefited from high levels of positive discussion all year long.
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Next year, more tech workers will speak out, following former Facebook employees Sean Parker and Chamath Palihapitiya, who have condemned social media’s addictive properties.
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
The web portal, which has put mobile technology at the heart of a plan to turn around its struggling fortunes, has turned to British teenager Nick D’Aloisio and Summly, which automatically summarises news stories for the small screen.
Consoles: Xbox One
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Given the Raptors' existing personnel, the Ibaka/Tucker additions qualify as massive defensive upgrades, giving coach Dwane Casey the tools he will need to grind out postseason wins if Lowry and DeMar DeRozan see their scoring efficiency dip as it has in years past.
The International Organization for Migration says the number of migrants and refugees entering Europe in 2015 has gone over the one million mark, the largest influx of its kind since the end of World War Two.
Yes. Mr Modi’s overnight ban on using high-value bank notes was a big shock, and seriously disrupted the economy. But it delivered rich political rewards, bolstering the premier’s image as a decisive leader willing to take tough action against corruption. With the next general elections due in 2019, Mr Modi will be tempted to deliver one more big bang to dazzle voters. Watch out for dramatic action against wealthy individuals holding properties in others’ names to hide their ownership.
Length-scale dependence of protein hydration-shell density
6.I’m 29. – Because 29 is like 20 years younger than 30.
The identity of the people buried in the cemetery is a mystery. The cemetery had been robbed in the past and no writing was found that indicates the names of those buried or their positions in life.
Halloween is just a few days away. Which means, if you haven’t gotten your costume or decorations sorted out yet, you might want to start doing that pretty soon.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
The banks' ability to return money to shareholders have declined. The slowing earning growth, high nonperforming loans and required deposits on the reserve have placed pressure on the banks in regards to capital supplement, said Guo Tianyong, director of the China Banking Research Center at the Central University of Finance and Economics.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
The memes included jokes about pedophilia, child abuse, sexual assault, and the Holocaust.
About this collection
During the same period, Braziland Russia slashed their holdings to USD 261.7 billion and USD 108.9 billion,respectively.